What is the pathway of the cerebrospinal fluid?

Beginning in the lateral ventricles, CSF flows through two passageways into the third ventricle. From the third ventricle it flows down a long, narrow passageway (the aqueduct of Sylvius) into the fourth ventricle.

Moreover, how is the cerebrospinal fluid circulated around the brain and spinal cord?

Cerebrospinal Fluid Circulation and Absorption. CSF is formed within the ventricles by small, delicate tufts of specialized tissue called the choroid plexus. From the fourth ventricle it passes through three small openings (foramina) into the subarachnoid space surrounding the brain and spinal cord.

How is cerebrospinal fluid formed and drained?

The cerebrospinal fluid (CSF) is produced from arterial blood by the choroid plexuses of the lateral and fourth ventricles by a combined process of diffusion, pinocytosis and active transfer. A small amount is also produced by ependymal cells.

How is the flow of CSF?

CSF is produced mainly by a structure called the choroid plexus in the lateral, third and fourth ventricles. CSF flows from the lateral ventricle to the third ventricle through the interventricular foramen (also called the foramen of Monro). Protection: the CSF protects the brain from damage by “buffering” the brain.

What is the path of CSF?

The CSF is formed in the lateral ventricles, circulates through the interventricular foramens into the third ventricle, and then via the cerebral aqueduct into the fourth ventricle.

What are the three functions of the cerebrospinal fluid?

Cerebrospinal fluid has three main functions: CSF protects brain and spinal cord from trauma. CSF supplies nutrients to nervous system tissue. CSF removes waste products from cerebral metabolism.

How does the cerebrospinal fluid flow?

CSF produced by the choroid plexuses in the lateral ventricles travels through interventricular foramina to the third ventricle, and then the fourth ventricle via the cerebral aqueduct and finally to the subarachnoid spaces via the median aperture (foramen of Magendie) of the fourth ventricle.

What are the components of cerebrospinal fluid?

Cerebrospinal fluid (CSF) is a clear, colourless ultrafiltrate of plasma with low protein content and few cells. The CSF is mainly produced by the choroid plexus, but also by the ependymal lining cells of the brain’s ventricular system.

How does CSF circulate through the brain?

Cerebrospinal fluid (CSF) is produced in the choroid plexus of the lateral ventricles and in the 4th ventricle of the brain. CSF then circulates through the ventricles of the brain and the subarachnoid space of the meninges.

Where is cerebrospinal fluid reabsorbed?

CSF occupies the subarachnoid space (between the arachnoid mater and the pia mater) and the ventricular system around and inside the brain and spinal cord. It fills the ventricles of the brain, cisterns, and sulci, as well as the central canal of the spinal cord.

What is the function of the cerebrospinal fluid?

While the primary function of CSF is to cushion the brain within the skull and serve as a shock absorber for the central nervous system, CSF also circulates nutrients and chemicals filtered from the blood and removes waste products from the brain.

How much CSF do adults have?

In normal adults, the CSF volume is 125 to 150 mL; approximately 20 percent of the CSF is contained in the ventricles; the rest is contained in the subarachnoid space in the cranium and spinal cord. The normal rate of CSF production is approximately 20 mL per hour.

What is the purpose of the cerebrospinal fluid?

The central nervous system (CNS) consists of the brain and spinal cord. Cerebrospinal fluid (CSF) is a clear, colorless liquid that surrounds and protects the CNS. It bathes the brain and spine in nutrients and eliminates waste products. It also cushions them to help prevent injury in the event of trauma.

What is fluid on the brain?

Although hydrocephalus was once known as “water on the brain,” the “water” is actually cerebrospinal fluid (CSF) — a clear fluid that surrounds the brain and spinal cord. The excessive accumulation of CSF results in an abnormal widening of spaces in the brain called ventricles.

What makes the blood brain barrier?

The blood–brain barrier is composed of high-density cells restricting passage of substances from the bloodstream much more than do the endothelial cells in capillaries elsewhere in the body.

What is the role of the blood brain barrier?

The barrier function of the blood–brain barrier is due to: (1) tight junctions that restrict movement of substances between the endothelial cells, (2) specific transport proteins that determine which substances can cross the barrier transcellularly and (3) enzymes that may degrade or alter substances prior to passage.

What is the role of the choroid plexus in the blood brain barrier?

The choroid plexus epithelium has functions as a barrier at the interface between the blood and cerebrospinal fluid (CSF) highly differentiated. The choroid plexus is located within cerebral ventricles and form the barrier called Blood-CDF-barrier (BCSFB).

What is obstructive hydrocephalus?

Hydrocephalus may be congenital or acquired. Communicating hydrocephalus occurs when cerebrospinal fluid (CSF) can still flow among the ventricles. Noncommunicating hydrocephalus, also called “obstructive” hydrocephalus, occurs when the flow of CSF is blocked.

What is increased intracranial pressure?

Intracranial pressure (ICP) is the pressure inside the skull and thus in the brain tissue and cerebrospinal fluid (CSF). The body has various mechanisms by which it keeps the ICP stable, with CSF pressures varying by about 1 mmHg in normal adults through shifts in production and absorption of CSF.

What forms the blood brain barrier?

Three cellular elements of the brain microvasculature compose the BBB-endothelial cells, astrocyte end-feet, and pericytes (PCs). Tight junctions (TJs), present between the cerebral endothelial cells, form a diffusion barrier, which selectively excludes most blood-borne substances from entering the brain.

Where is the choroid plexus?

Location. There are four choroid plexuses in the brain, one in each of the ventricles. Choroid plexus is present in all parts of the ventricular system except for the cerebral aqueduct, the frontal horn and the occipital horn of the lateral ventricles.

What is communicating hydrocephalus?

Communicating hydrocephalus, also known as non-obstructive hydrocephalus, is caused by impaired cerebrospinal fluid reabsorption in the absence of any CSF-flow obstruction between the ventricles and subarachnoid space.

What is the arachnoid granulation?

Arachnoid granulations, also known as a Pacchionian granulation, are projections of the arachnoid membrane (villi) into the dural sinuses that allow CSF entrance from the subarachnoid space into the venous system.

What does the meninges do?

Detailed Information: The Meninges and Cerebrospinal Fluid. The meninges are three layers of protective tissue called the dura mater, arachnoid mater, and pia mater that surround the neuraxis. The meninges of the brain and spinal cord are continuous, being linked through the magnum foramen.

Originally posted 2022-03-31 06:00:52.

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