Grapefruit might interact with some “statins” including lovastatin (Mevacor), simvastatin (Zocor), and atorvastatin (Lipitor). Grapefruit juice does not interact with other “statins” including pravastatin (Pravachol), fluvastatin (Lescol), and rosuvastatin (Crestor).
Subsequently, one may also ask, what drugs are affected by grapefruit?
What medicines should not be taken with grapefruit juice?
Some statins (cholesterol-lowering drugs): lovastatin (Mevacor), atorvastatin (Lipitor), simvastatin (Zocor, Vytorin). (Other statins such as fluvastatin (Lescol), pravastatin (Pravachol), and rosuvastatin (Crestor) have little or no interaction with grapefruit juice.) Antihistamines: fexofenadine (Allegra)
Why can t you eat grapefruit while taking some medicine?
Eating grapefruit or drinking grapefruit juice affects how your body processes certain medicines. This makes it more likely that you will experience side effects from the medicine, or that your medicine won’t be effective. Certain types of oranges, such as pomelo and seville, can also cause similar effects.
Can you eat grapefruit while taking medication?
Drugs that interact with grapefruit are taken by mouth. The degree of the grapefruit effect can vary. With some drugs, just one serving of grapefruit can make it seem like a person is taking multiple doses of the drug. This interaction can occur even if grapefruit is eaten many hours before taking the medication.
What medicines do grapefruit interfere with?
Grapefruit Juice and Some Drugs Don’t Mix
Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin).
Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine).
Some organ-transplant rejection drugs, such as Sandimmune and Neoral (both cyclosporine).
What is the effect of grapefruit on medication?
The authors report that grapefruit, grapefruit juice, and some other citrus fruit, including Seville oranges, limes and pomelos, contain a class of chemical called furanocoumarins. Furanocoumarins inhibit an enzyme, cytochrome P450 3A4, that is responsible for the inactivation of approximately half of all drugs.
How does grapefruit affect high blood pressure?
Statins are medicines that lower your cholesterol. Grapefruit or grapefruit juice affects some statins. Do not drink grapefruit juice if you’re taking simvastatin. Grapefruit juice increases the level of simvastatin in your blood and makes side effects more likely.
Why grapefruit is bad for you?
Drinking grapefruit juice together with certain medicines can increase blood levels of the drug to harmful levels, according to an editorial in the January issue of the journal Nature Medicine. Grapefruit juice inhibits a chemical in the intestine needed to break down many drugs in the body.
Can I eat grapefruit while taking levothyroxine?
Grapefruit juice may slightly delay the absorption of levothyroxine, but it seems to have only a minor effect on its bioavailability. Accordingly, the clinical relevance of the grapefruit juice-levothyroxine interaction is likely to be small.
Why does grapefruit help you lose weight?
Grapefruit can be part of a healthy weight loss diet because it’s nutritious, not because of any mysterious fat-burning properties. A half grapefruit or a glass of grapefruit juice before meals may help fill you up, so you’ll eat fewer calories at meals and potentially lose weight.
Do oranges interact with medications?
In all such cases there are alternative medications available that will not interact with grapefruit and the other citrus fruits that contain furanocoumarins, the culprit behind the “grapefruit juice effect,” Derendorf says. Sweet oranges, such as navel and Valencia, do not contain furanocoumarins.
Why can’t you eat grapefruit when taking a statin?
Grapefruit contains a chemical that interferes with your body’s ability to break down or metabolize certain statin medications. When statin takers eat large amounts of grapefruit, the level of statins in their blood can increase, raising the possibility of side effects.
Why can you not eat grapefruit with statins?
When the action of these enzymes is blocked (as by grapefruit juice), more of the drugs get into the body, and the blood levels of these medications increase. This can lead to toxic side effects from Lipitor, such as liver or muscle damage.
What medications interact with citrus fruit?
According to an article published in the Canadian Medical Association Journal in November 2012, as many as 85 prescription drugs may interact with substances found in grapefruit, grapefruit juice and other citrus fruits such as limes and Seville oranges (used in marmalade), causing adverse health effects.
Why is grapefruit bad for diabetics?
Drinking grapefruit juice improved insulin sensitivity in mice, regardless of their diet (in people, reduced insulin sensitivity can be a sign of impending diabetes). Grapefruit juice lowered blood sugar as effectively as metformin, a drug widely used to treat people with type 2 diabetes.
Can you eat grapefruit while taking metformin?
Takeaway. Grapefruit does lead to negative interactions with some medications. However, there are no case studies in which consuming grapefruit juice while taking metformin led to adverse effects in humans.
What are the benefits of eating grapefruit?
The powerful nutrient combination of fiber, potassium, lycopene, vitamin C, and choline in grapefruit all help to maintain a healthy heart. The DASH diet, designed to reduce blood pressure through dietary options, includes grapefruit as a recommended food.
Why is a grapefruit bitter?
In the case of grapefruit, the explanation may lie not with the salt, but with the fruit. Redder grapefruits contain less naringin, and therefore taste less bitter. This means that there is less of an incentive to curb bitterness with a dash of salt.
Can I take amlodipine with grapefruit juice?
You can safely drink small amounts of grapefruit juice, but if you drink close to a quart or more than that each day, you will put yourself at serious risk. Drinking too much grapefruit juice while on amlodipine can cause the same side effects as if you were taking massive amounts of the drug.
Can I eat grapefruit?
If you accidentally consume a small amount of grapefruit, it isn’t likely to affect your medication. To be safe, restrict drinking and eating grapefruit if you take statins until you talk to your doctor about the risk. It’s also recommended to avoid grapefruit juice when taking medication.
What are the benefits of grapefruit juice?
Grapefruit is a tropical citrus fruit known for its sweet and somewhat sour taste. It’s rich in nutrients, antioxidants and fiber, making it one of the healthiest citrus fruits you can eat. Research shows that it may have some powerful health benefits, including weight loss and a reduced risk of heart disease.
Can you eat grapefruit while taking losartan?
While you are taking this medicine, you should avoid eating grapefruit or drinking grapefruit juice. You may choose an alternative citrus beverage (such as orange juice). These effects can occur even if grapefruit is not consumed at the same time of the losartan dose.
What foods react with medications?
5 Common Food-Drug Interactions
Grapefruit Juice. “Grapefruit juice has the ability to interact with medications in various ways,” says Plogsted.
Green Leafy Vegetables. Blood-thinning drugs such as Coumadin® (warfarin) interfere with vitamin K-dependent clotting factors.